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Naledi and 380+ others use tretinoin daily

Tretinoin Cream 0.05%, Tretiheal 20g & Tretin 30g for Dark Spots

Tretinoin cream 0.05% is a vitamin A based retinoid that helps manage acne, unclog pores, and refine uneven skin texture. It is available in Tretiheal 20g and Tretin 30g, with simple online ordering and delivery available across South Africa through skincareproduct.co.za.
R 379.99R 479.99 Save 21%
Anti-ageing gold standard
Most prescribed strength
Night routine
Fades dark spots
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Kligman Anti-Ageing Protocol

Kligman Anti-Ageing Protocol

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Tretinoin Cream 0.05%Melalite Hydroquinone 4%Sunroof SPF 50 Sunscreen
3 items
R872.97 R969.97 Save R97.00
payfast — accepted at SkinCare Product SAvisa — accepted at SkinCare Product SAmastercard — accepted at SkinCare Product SApayfast eft — accepted at SkinCare Product SAmobicred — accepted at SkinCare Product SA
Free shipping above R 1,500
Manufacturer Healing Pharma / Helios Pharmaceuticals
SKU TRET-CRM-005-20

Tretinoin cream usp 0.05% is considered a moderate strength retinoid that is often selected by users who need stronger results than lower strengths. It is commonly used for acne, uneven tone, and visible skin texture concerns when basic routines are no longer enough. This formulation contains tretinoin, a vitamin A derivative that helps speed up the natural renewal process of the skin. As old cells shed faster, pores stay clearer, breakouts reduce, and the surface of the skin becomes smoother. With regular use, it also helps improve dull tone, reduce dark spots, and support firmer looking skin. Tretiheal 0.05% 20g by Healing Pharma and Tretin 0.05% 30g by Hegde and Hegde are widely chosen options. Both provide the same 0.05% strength, allowing users to select based on preferred size while targeting similar skin concerns.

  • • Helps reduce acne and prevent future breakouts
  • • Supports clearing of blackheads and whiteheads
  • • Improves rough and uneven skin texture
  • • Helps fade dark spots and pigmentation
  • • Supports firmer looking skin through collagen support
  • • Reduces early signs of fine lines
  • • Promotes clearer and more balanced skin tone

Who is this for?

Individuals with acne prone or oily skin, people dealing with clogged pores or breakouts, users who want smoother and clearer skin, those with pigmentation or uneven tone, users stepping up from tretinoin cream 0.025%, and individuals targeting early signs of ageing.

Begin with a patch test to check skin tolerance. Wash your face with a gentle cleanser and let it dry fully before applying. Wait around 15 to 20 minutes, then use a small pea sized amount and spread it evenly in a thin layer. Apply only at night and keep away from sensitive areas like eyes, lips, and corners of the nose. Wash your hands after use. Start with 2 to 3 applications per week, then slowly increase frequency as your skin adjusts. Use a moisturiser after application to reduce dryness. Daily sunscreen use is essential, as tretinoin makes the skin more sensitive to sunlight. Avoid strong sun exposure during treatment. Application routine — Week 1 to 2: use twice weekly at night. Week 3 to 4: increase to three nights weekly if tolerated. Week 5 onward: apply on alternate nights. Long term: use nightly once skin builds tolerance. Important: Always apply at night and use sunscreen during the day.

How it works

Tretinoin 0.05% works by speeding up how quickly the skin replaces old cells with new ones. This helps clear blocked pores, reduce oil buildup, and prevent new breakouts. At the same time, it supports collagen activity, which improves texture, tone, and overall skin appearance with continued use.

Tretinoin (all trans retinoic acid) — 0.05%

Vitamin A derivative that supports faster skin renewal and helps improve collagen activity.

Inactive ingredients

  • • Purified water
  • • Stearic acid
  • • Stearyl alcohol
  • • Propylene glycol
  • • Isopropyl myristate
  • • Polyoxyl 40 stearate
  • • Xanthan gum
  • • Sorbic acid
  • • Butylated hydroxytoluene
  • • Emulsifiers
  • • Preservatives

Important

  • • Skin may feel dry, red, or start peeling during early use
  • • Use sunroof sunscreen lotion SPF 50 every day
  • • Limit sun exposure while using tretinoin
  • • Avoid applying near sensitive areas or irritated skin
  • • Do not use during pregnancy
  • • Avoid applying with benzoyl peroxide at the same time
  • • Do not combine with salicylic acid or strong exfoliating products
  • • Avoid harsh skincare that may increase irritation
  • • Keep between 20°C and 25°C
  • • Store away from heat and sunlight
  • • Close the tube properly after each use
  • • Keep out of reach of children

SA regulatory note: Tretinoin is a regulated clinical-strength active ingredient. Always follow the safety precautions on the pack and consult a healthcare professional before use.

This information is general guidance only and should not replace advice from a healthcare professional.

  • Weeks 1 to 3 slight dryness or temporary breakouts may occur
  • Weeks 4 to 8 smoother texture with fewer new spots
  • 6 to 12 weeks clearer tone and visible improvement

Note: Regular use gives better long term results.

Common

  • • Dryness
  • • Redness
  • • Peeling
  • • Irritation
  • • Mild burning sensation
  • • Sun sensitivity

Less Common

  • • Temporary breakouts
  • • Skin flaking
  • • Mild itching
  • • Slight swelling

For delivery and return details, please refer to our Shipment & Return Policy.

How does it compare?

Feature You're viewingTretiheal Tretinoin Cream 0.05% Tretin 0.05% Cream
BrandHealing Pharma India Pvt LtdHegde and Hegde Pharmaceutica LLP
ManufacturerTretihealTretin
StrengthTretinoin 0.05%Tretinoin 0.05%
FormTopical creamTopical cream
Net Quantity20 g30 g
Country of OriginIndiaIndia
Packaging TypeTubeTube
Suitable ForUsers moving from lower strengthUsers preferring larger size
Main BenefitsAcne care and skin renewalAcne care and skin renewal
UsageNight applicationNight application

About this product

You can buy it directly from skincareproduct.co.za with delivery available across South Africa.
Yes, you can order it online from our store without needing a prescription.
The cost depends on the option you select. You can check the latest price on the product page.
Yes, you can order it online easily without visiting a physical pharmacy.
It is generally safe when used correctly, but some irritation may occur during early use.
Tretinoin 0.05% is usually considered more active, while adapalene may feel gentler for some users.
Many users move to 0.05% after building tolerance, as it provides stronger and more noticeable results.

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