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Zanele and 320+ others use triluma daily

Triluma Cream 15g with Hydroquinone, Tretinoin, & Fluocinolone Acetonide

Triluma Cream 15g is a prescription strength triple combination cream developed for facial melasma, hyperpigmentation, dark spots, and uneven skin tone. It contains Hydroquinone USP 4%, Tretinoin USP 0.05%, and Fluocinolone Acetonide IP 0.01%. Customers across South Africa can buy Triluma Cream 15g online from skincareproduct.co.za with reliable nationwide delivery.
R 549.00R 650.00 Save 16%
Triple-action melasma treatment
Fades stubborn dark patches
Supports skin cell renewal
Built-in calming agent
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Melasma Care Kit

Melasma Care Kit

Treat + Protect
Triluma Cream 15g (Galderma)Aziderm Azelaic Acid 20% 15g (Micro Labs)Sunroof SPF 50 Sunscreen
3 items
R1,025.08 R1,138.98 Save R113.90
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Manufacturer Galderma
SKU TRL-CRM-15

Triluma Cream 15g by Galderma is formulated to help manage moderate to severe facial melasma and other stubborn pigmentation concerns. Its triple combination formula works on different causes of skin discolouration to help improve uneven skin tone and reduce the appearance of persistent dark patches. Hydroquinone helps reduce excess melanin production, while Tretinoin supports faster skin renewal. Fluocinolone Acetonide helps calm skin irritation that may occur during treatment. Together, these ingredients help promote a brighter and more even looking complexion.

  • • Triple combination cream developed by Galderma
  • • Contains Hydroquinone 4%, Tretinoin 0.05%, and Fluocinolone Acetonide 0.01%
  • • Helps improve melasma and facial hyperpigmentation
  • • Helps reduce dark spots and uneven skin tone
  • • Supports healthy skin cell renewal
  • • Promotes smoother and brighter looking skin
  • • Supplied in a convenient 15g tube

Who is this for?

Adults with melasma, facial hyperpigmentation, dark spots, or uneven skin tone. People who want a targeted short term treatment for visible pigmentation on the face. Pigmentation associated with sun exposure, hormonal changes, or post inflammatory skin marks. Not suitable during pregnancy or while breastfeeding.

Wash your face with a mild cleanser and allow the skin to dry completely before application. Wait around 10 to 15 minutes, then apply a pea sized amount of Triluma Cream to the affected areas only. Spread a thin layer gently and avoid contact with the eyes, lips, nostrils, and other sensitive areas. Apply Triluma Cream once each evening unless instructed differently by your healthcare professional. A gentle moisturiser may be used about 20 minutes after application if your skin feels dry. Wear SPF 30 or higher sunscreen every morning and reduce unnecessary sun exposure to help maintain treatment results.

How it works

Triluma Cream contains three active ingredients that perform different roles during treatment. Hydroquinone helps reduce the formation of excess melanin. Tretinoin encourages faster skin cell turnover, allowing pigmented skin cells to shed more efficiently. Fluocinolone Acetonide helps calm inflammation and improve treatment tolerance. These ingredients work together to target facial pigmentation through different pathways, making the formula suitable for short term treatment of melasma and other pigmentation concerns.

Hydroquinone — USP 4%

  • • Helps reduce the formation of excess melanin
  • • Fades melasma and stubborn dark patches

Tretinoin — USP 0.05%

  • • Encourages faster skin cell turnover
  • • Helps pigmented skin cells shed more efficiently

Fluocinolone Acetonide — IP 0.01%

  • • Helps calm inflammation
  • • Improves treatment tolerance

Inactive Ingredients

  • • Cetostearyl Alcohol
  • • Propylene Glycol
  • • Stearic Acid
  • • Glycerin
  • • Sodium Metabisulphite
  • • Purified Water

Important

  • • For external use only
  • • Avoid contact with the eyes, lips, nostrils, and mucous membranes
  • • Do not apply to broken, irritated, or sunburned skin
  • • Apply SPF 30 or SPF 50 sunscreen every day while using this product
  • • Limit prolonged sun exposure during treatment
  • • Stop using the cream if severe irritation or an allergic reaction develops
  • • Do not use during pregnancy or while breastfeeding
  • • Avoid use if you have a sulphite allergy
  • • Use only for the recommended treatment period — do not continue long term use without professional advice
  • • Avoid combining with strong exfoliating products unless advised by a healthcare professional
  • • Keep out of reach of children
  • • Store below 25°C in a cool, dry place away from direct sunlight
  • • Keep the cap tightly closed and store in the original packaging
  • • Check the expiry date before use

This information is general guidance only and should not replace advice from a healthcare professional.

  • Weeks 1 to 2 :Skin begins adjusting to the treatment. Mild dryness, peeling, or slight redness can occur; visible pigmentation usually remains unchanged.
  • Weeks 3 to 5 :Dark patches may begin fading gradually. The complexion can start looking more even and the skin may feel softer.
  • Weeks 6 to 8 :Pigmentation may continue to improve, making melasma and dark spots less noticeable. Results vary from person to person.

Note: Using Triluma Cream consistently each evening and applying SPF 30 or higher sunscreen every day helps maintain the best possible results.

Common

  • • Dry or flaky skin
  • • Slight redness
  • • Mild peeling
  • • Light burning or stinging after application
  • • Itchy skin
  • • Temporary discomfort
  • • Increased sensitivity while the skin adjusts

Less Common

  • • Ongoing redness
  • • Thinning of the treated skin with extended use
  • • Allergic reaction
  • • Swelling around the application area
  • • Ochronosis following inappropriate long term use
  • • Greater sensitivity to sunlight

Most people experience only mild side effects during the first few weeks of treatment. If symptoms become severe or you develop signs of an allergic reaction, stop using Triluma Cream and consult a healthcare professional.

For delivery and return details, please refer to our Shipment & Return Policy.

How does it compare?

Feature You're viewingTriluma Cream Skinshine Cream Hydroquinone 4%
ActivesHydroquinone 4% + Tretinoin 0.05% + FluocinoloneHydroquinone + Tretinoin + MometasoneHydroquinone only
Efficacy for melasmaHigh (triple combination)HighHigh (gold standard)
Soothing agentFluocinolone (mild)Mometasone (potent)None
Skin renewalYes (tretinoin)Yes (tretinoin)No
Treatment lengthShort term (up to 8 weeks)Short termCycling required (3-4 months)
PregnancyNoNoNo

About this product

Triluma Cream 15g is used to help manage melasma, facial hyperpigmentation, dark spots, and uneven skin tone. Its triple combination formula targets excess pigmentation while supporting a clearer complexion.
Regular use may help reduce visible pigmentation, improve skin texture, and promote a more even skin tone. It also supports natural skin renewal in affected areas.
Triluma Cream contains three active ingredients: Hydroquinone USP 4%, Tretinoin USP 0.05%, and Fluocinolone Acetonide IP 0.01%. Each ingredient plays a different role in treating facial pigmentation.
Apply a thin layer to clean, dry skin once every evening. Use only on the affected areas and wear SPF 30 or higher sunscreen during the day to protect your skin.
Triluma Cream is generally intended for short term treatment. Many people use it for up to eight weeks, or as directed by their healthcare professional.
Yes. It may help improve dark spots caused by melasma as well as post inflammatory pigmentation that remains after acne has healed.
Some users may experience dryness, peeling, redness, mild burning, or itching during the first few weeks. These effects often become less noticeable as the skin adjusts to treatment.
No. Triluma Cream is not recommended during pregnancy or while breastfeeding. Speak with your healthcare professional about suitable alternatives.
You can order Triluma Cream 15g online from skincareproduct.co.za with delivery available across South Africa, subject to stock availability.
Triluma Cream is supplied in a 15g tube, making it suitable for targeted application on areas affected by melasma and facial hyperpigmentation.

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